Research progress on modifying sleep deprivation with Modafinil to improve flight operation ability of pilots
10.3760/cma.j.cn113854-20201230-00177
- VernacularTitle:莫达非尼改善睡眠剥夺对飞行员飞行操作能力的研究进展
- Author:
Jun LIU
1
;
Xiangyang ZHANG
1
;
Lue DENG
1
Author Information
1. 空军特色医学中心空天医学总体论证研究室，北京 100142
- Publication Type:Journal Article
- Keywords:
Central nervous system agents;
Sleep deprivation;
Cognition;
Review;
Modafinil
- From:
Chinese Journal of Aerospace Medicine
2021;32(2):124-128
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To conduct the research progress on applying Modafinil to modify the sleep deprivation and provide reference to the further research on improving sleep deprived pilot′s flight ability by taking psychotropic medications.Literature resource and selection:Relevant articles and scientific reports published in China and abroad.Literature quotation:Thirty-five published papers were cited.Literature synthesis:The negative effects of sleep deprivation on pilots′ alertness, cognitive function, and flight operation ability were briefly reviewed in this article, and the improvement in the flight operation ability of sleep deprived pilots by taking Modafinil verified by the computer-simulated flight was summarized. In wartime, pilots suffered from the decline of alertness, impairment of such cognitive functions as concentration and memory and degenerative flight operation ability caused by sleep deprivation in cross time zone and long-distance flights. Modafinil can effectively alleviate the fatigue of pilots under sleep deprivation, sustain their central nervous alertness, significantly improve their cognitive function as a cognitive enhancer, and reduce the influences on pilot′s operation ability that caused by sleep deprivation in simulated flight.Conclusions:The rational use of Modafinil is an important emergency measure to sustain pilot′s alertness, alleviate fatigue and improve cognitive ability, as well as to maintain his flight operation ability. The further research on resisting sleep deprivation by psychotropic medications to maintain flight operation ability would be of great significance to the improvement on Chinese military medical support.
