A case of serotonin syndrome induced by fluoxetine combined with bupropion and tandospirone
10.3760/cma.j.cn113661-20240510-00143
- VernacularTitle:氟西汀联合安非他酮、坦度螺酮致5-羟色胺综合征1例
- Author:
Huanhuan YAN
1
;
Mei BAI
;
Xiaowei LUO
;
Huijie DU
;
Xin ZHANG
;
Lu YANG
;
Yang YANG
;
Wei WANG
;
Shuqin JIA
;
Jinxuan WEI
Author Information
1. 贵州医科大学临床医学院，贵州 550001
- Publication Type:Journal Article
- Keywords:
Fluoxetine;
Bupropion;
Serotonine syndrome;
5-hydroxytryptamine;
Drug reaction
- From:
Chinese Journal of Psychiatry
2025;58(3):220-223
- CountryChina
- Language:Chinese
-
Abstract:
Serotonin syndrome (SS), also known as serotonin toxicity, is a rare but life-threatening drug reaction syndrome. This case involves a 17-year-old female patient who developed tremors, fatigue, and tachycardia after taking fluoxetine combined with bupropion and tandospirone for five days. SS was highly suspected, and her symptoms improved following treatment targeted at serotonin syndrome. This case is reported to raise awareness among clinicians about the potential adverse reactions of drug combinations, the importance of early identification of SS symptoms, and precautions when prescribing combined medications to avoid serious consequences.
