Lamotrigine augmentation in the treatment of schizophrenia with body dysmorphic symptoms: a case report
10.3760/cma.j.cn113661-20231127-00228
- VernacularTitle:拉莫三嗪增效治疗伴有躯体变形症状的精神分裂症1例
- Author:
Linlin MING
1
;
Xianghe WANG
1
;
Chengcheng PU
1
Author Information
1. 北京大学第六医院 北京大学精神卫生研究所 国家卫生健康委员会精神卫生学重点实验室（北京大学）国家精神心理疾病临床医学研究中心（北京大学第六医院），北京100191
- Publication Type:Journal Article
- Keywords:
Body dysmorphic disorders;
Schizophrenia;
Lamotrigine;
Selective serotonin reuptake inhibitors
- From:
Chinese Journal of Psychiatry
2024;57(8):520-524
- CountryChina
- Language:Chinese
-
Abstract:
Body dysmorphic symptom is a symptom of obsessive-compulsive-related disorder and can be one of the symptoms of schizophrenia, causing severe distress and impairment of social functioning. Selective serotonin reuptake inhibitors (SSRIs) are the first line of therapeutic agents for body dysmorphic disorder (BDD). The combination of SSRIs and adjuvant drug therapy is a commonly used strategy for patients when their treatment is ineffective. This article reported a case of a young female patient with schizophrenia accompanied by body dysmorphic symptoms who was effectively treated with lamotrigine augmentation therapy, and discussed the clinical features of BDD, pharmacotherapy, potential pharmacological effects and adverse effects of lamotrigine based on the literature, in order to provide new perspectives on the treatment of body dysmorphic symptoms for clinical staff.
