Research progress on theta burst transcranial magnetic stimulation in the treatment of refractory depression

VernacularTitle:Theta脉冲刺激治疗难治性抑郁症的研究进展
Author: Rongxu ZHANG ¹ ; Dong HUANG ¹ ; Xiaodong SONG ¹ ; Shuming ZHONG ¹ ; Yanbin JIA ¹
Author Information

1. 暨南大学附属第一医院精神医学科，广州510630
Publication Type:Journal Article
Keywords: Depressive disorder; Transcranial magnetic stimulation; Physical therapy
From: Chinese Journal of Psychiatry 2024;57(1):54-60
CountryChina
Language:Chinese
Abstract: Depression is a psychiatric disorder characterized by persistent depressed mood with high morbidity, suicidality, and mortality, in which treatment-resistant depression (TRD)is characterized by ineffective treatment with at least two types of antidepressants. Burst Stimulation (TBS), also known as theta burst stimulation (TBS), is a non-invasive physical therapy that includes intermittent TBS(iTBS) and continuous TBS(cTBS). Among them, iTBS has good antidepressant efficacy in TRD patients and can effectively improve their depressive mood. Therefore, this article will review the clinical application and related mechanisms of iTBS in TRD, to provide clinical guidance and theoretical support for TBS in treating of depression.