Clinical value of repeated endoscopic ultrasound-guided fine-needle aspiration
10.3760/cma.j.cn321463-20240729-00518
- VernacularTitle:重复超声内镜引导细针穿刺抽吸术的临床价值
- Author:
Jun GAO
1
;
Xinyan XU
;
Ruiguang MA
;
Miaomiao MA
;
Zhen LI
;
Ning ZHONG
Author Information
1. 山东阳光融和医院消化内科，潍坊 261061
- Publication Type:Journal Article
- Keywords:
Punctures;
Endoscopic ultrasound;
Fine needle aspiration;
Neoplastic lesion
- From:
Chinese Journal of Digestive Endoscopy
2025;42(3):207-211
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the diagnostic value of repeated endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in patients with suspected neoplastic lesions.Methods:Patients with clinically suspected neoplastic lesions, who did not receive a definitive diagnosis following the initial EUS-FNA and subsequently underwent repeated EUS-FNA, were collected from the gastrointestinal endoscopy center of Qilu Hospital of Shandong University from January 2018 to October 2023. The ultrasonographic endoscopic images, pathology, and follow-up data were reviewed. Patients with confirmed diagnoses following repeated EUS-FNA were analyzed to determine the diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of repeat EUS-FNA for tumor and non-neoplastic lesions.Results:A total of 36 patients with space-occupying lesions in different parts were included in the study, and the final diagnosis was 80.6% (29/36) of tumor lesions and 19.4% (7/36) of non-tumor lesions. Among these, 34 patients received definitive diagnoses. The diagnostic sensitivity of repeated EUS-FNA for tumor was 82.8% (24/29), the specificity was 100.0% (7/7), the positive predictive value was 100.0% (24/24), the negative predictive value was 58.3% (7/12), and the accuracy was 86.1% (31/36).Conclusion:Repeated EUS-FNA proves to be an effective and practical approach for cases where is suspicion of neoplastic lesions and the initial EUS-FNA pathology findings remain inconclusive.
