Research progress on the application of human amniotic membrane in ocular fundus diseases
10.3760/cma.j.cn511434-20241210-00480
- VernacularTitle:人羊膜在眼底疾病中应用的研究进展
- Author:
Fangxing ZHU
1
;
Jiandong LIU
;
Rongyu GAO
;
Jiantao REN
;
Xuequan SUN
;
Xudong HUANG
Author Information
1. 山东第二医科大学临床医学院 山东第二医科大学, 潍坊 261041
- Publication Type:Journal Article
- Keywords:
Amniotic membrane;
Macular hole;
Rhegmatogenous retinal detachment;
Age related macular degeneration;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2025;41(4):324-328
- CountryChina
- Language:Chinese
-
Abstract:
Human amnion (hAM), as a biomaterial, has made significant progress in the field of ophthalmology, particularly in the treatment of retinal diseases. hAM possesses biological properties such as promoting tissue repair, inhibiting inflammation and neovascularization, and reducing fibrosis, which have led to its promising clinical outcomes in treating macular holes, retinal detachment, proliferative vitreoretinopathy, optic disc depression-related macular detachment, and age-related macular degeneration. The application of hAM can improve surgical success rates and promote vision recovery, with no significant rejection reactions observed due to its low immunogenicity. Nevertheless, the use of hAM still faces challenges in optimizing preparation and storage techniques, enhancing therapeutic efficacy, and reducing the risk of infectious disease transmission. Future research should focus on addressing these issues to further promote the application of hAM in retinal disease treatment and enhance its effectiveness.
