Research progress on the correlation between bronchopulmonary dysplasia and retinopathy of prematurity
10.3760/cma.j.cn511434-20240925-00357
- VernacularTitle:支气管肺发育不良与早产儿视网膜病变的相关性研究进展
- Author:
Caiyu ZHANG
1
;
Huiqing SUN
1
Author Information
1. 郑州大学附属儿童医院新生儿内科, 郑州 450018
- Publication Type:Journal Article
- Keywords:
Bronchopulmonary dysplasia;
Retinopathy of prematurity;
Angiogenesis;
Premature infants;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2025;41(2):163-168
- CountryChina
- Language:Chinese
-
Abstract:
Bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) are common and critically important diseases of preterm infants. The common feature of both conditions is altered angiogenesis and pathological changes in the case of incomplete organ development. The interaction of multiple factors leads to abnormal angiogenesis, which not only increases the possibility of comorbidity of BPO and ROP, but also reveals the potential co-pathogenesis between the two. However, the specific mechanism of this angiogenic balance in the occurrence and development of BPD or ROP is still unclear, and there are no animal models to explore the pathogenesis of both diseases. At present, effective prevention measures for BPO and ROP are still lacking, and treatment methods mainly rely on drug therapy and surgery. In the future, more studies should be conducted to find common therapeutic targets for factors affecting angiogenesis, so as to provide better treatment options for BPD and ROP and improve the effectiveness of treatment.
