Recent advances in mismatch negativity of schizophrenia
10.3760/cma.j.cn113661-20200922-00412
- VernacularTitle:精神分裂症的失匹配负波研究进展
- Author:
Shuqi XU
1
;
Jinling WAN
1
;
Jinsheng MA
1
;
Xueyi WANG
1
;
Ran WANG
1
Author Information
1. 河北医科大学第一医院精神卫生中心 河北医科大学精神卫生研究所 河北省脑老化与认知神经科学实验室，石家庄050031
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Evoked potentials;
Mismatch negativity
- From:
Chinese Journal of Psychiatry
2021;54(4):300-304
- CountryChina
- Language:Chinese
-
Abstract:
Mismatch negativity (MMN) is an endogenous component of event-related potential that occurs with deviation stimulus. It has been widely used as a biomarker in schizophrenia-related researh. Studies have shown that MMN is correlated with early diagnosis of mental illness, cognitive impairment, and social-behavioral dysfunction in psychiatric patients. Further studies on relevant mechanisms would be conducive to understand the electrophysiological, cognitive, and behavioral changes of mental diseases and provide a new treatment strategy. This review introduces the latest progress in basic research and clinical application of MMN in schizophrenia, discusses the future research direction of MMN, and provides evidence for further research.
