Effects of emotional cues on event-based prospective memory in patients with obsessive-compulsive disorder
10.3760/cma.j.cn113661-20210201-00071
- VernacularTitle:情绪线索对强迫症事件性前瞻记忆的影响
- Author:
Qian LIU
1
;
Jie FAN
;
Jie XIA
;
Xiang WANG
;
Mingtian ZHONG
;
Xiongzhao ZHU
Author Information
1. 中南大学湘雅二医院医学心理中心，长沙 410011
- Publication Type:Journal Article
- Keywords:
Obsessive-compulsive disorder;
event-based prospective memory;
emotional enhancement effect
- From:
Chinese Journal of Psychiatry
2021;54(6):434-439
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of emotional cues on prospective memory (PM) in obsessive-compulsive disorder (OCD) patients.Methods:From December 2014 to November 2019, 157 patients with obsessive-compulsive disorder (OCD) and 119 healthy controls (HC) matched for age, gender and intelligence participated in the study. A laboratory event-based PM paradigm was used to assess the PM function. The PM Accuracy (PM acc) of prospective memory pictures with different emotional cues in the two groups was investigated by a mixed design of 2 (group: OCD group, HC group)×3 (emotional cue attributes: positive, neutral, and negative). Correlation analysis was used to explore the relationship between PM acc and clinical variables in patients with OCD.Results:Repeated measures ANOVA showed that the main effect of emotional cues was not significant ( F=0.377, P>0.05), the difference between the two groups was significant ( F=8.863, P<0.01, η 2=0.030), and the PM acc of the OCD group was lower than HC. The interaction was significant ( F=3.261, P<0.05, η 2=0.012). Further simple effect analysis showed that in the HC group, PM acc with positive emotional cues and negative emotional cues were significantly greater than PM acc with neutral emotional cues (Cohen′s d values are 2.29 and 2.94). There was no significant difference between PM acc with positive emotional cues and PM acc with negative emotional cues. In the OCD group, PM acc with negative emotional cues was significantly greater than PM acc with positive and neutral emotional cues (Cohen′s d values are 1.57 and 1.14). There was no significant difference between PM acc with positive emotional cues and PM acc with neutral emotional cues. Correlation analysis showed that PM acc with positive and negative emotional cues of OCD patients were significantly positively correlated with state anxiety level ( r>0.200, P<0.01). There was no significant correlation between PM acc with neutral emotional cues and anxiety level. Conclusion:OCD patients had impaired prospective memory, mainly manifested as impaired prospective memory emotional enhancement effect, only negative emotion enhancement effect showed. In contrast, positive emotion has no enhancement effect on the prospective memory of OCD patients.
