Current status of interventional therapy for hepatic encephalopathy associated with spontaneous portosystemic shunts
10.3760/cma.j.cn501113-20241116-00583
- VernacularTitle:自发性门静脉-体循环分流相关肝性脑病的介入治疗现状
- Author:
Zihong CAI
1
;
Qiao KE
;
Yubing JIAO
;
Xiadi WENG
;
Jian HE
;
Xinhui HUANG
;
Ling LI
;
Wuhua GUO
Author Information
1. 福建医科大学孟超肝胆医院介入科，福州 350000
- Publication Type:Journal Article
- Keywords:
Hepatic encephalopathy;
Spontaneous portosystemic shunts;
Interventional therapy
- From:
Chinese Journal of Hepatology
2025;33(6):595-600
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic encephalopathy (HE) is a kind of neuropsychiatric syndrome caused by acute or chronic liver failure or portosystemic venous shunt (hereinafter referred to as portosystemic shunt), which can lead to the occurrence of functional impairment, personality and behavioral abnormalities, coma, and even death. Most patients with cirrhosis combined with HE have spontaneous portosystemic shunt (SPSS), especially those with recurrent or persistent HE. Internal medicine's current standard of treatment for HE associated with SPSS in cirrhotic patients is unsatisfactory, and even after treatment, recurrent HE episodes may still occur. Although interventional therapy has shown significant results and has been applied in clinical practice for many years for SPSS-associated HE, the number of treatment-related cases is relatively small, and there is a lack of large samples and well-designed research. Currently, interventional therapy for SPSS-associated HE in patients with cirrhosis is still under continuous exploration.
