Psychological outcomes of patients with cutaneous vascular compromise caused by hyaluronic acid injection after sequential therapy
10.3760/cma.j.cn114657-20250409-00083
- VernacularTitle:透明质酸注射并发皮肤血运障碍患者序贯治疗前后心理状况变化分析
- Author:
Guiwen ZHOU
1
;
Hongfan DING
1
;
Qiang FU
1
;
Qian WU
1
;
Pianpian LIN
1
;
Guangdi LI
1
;
Xiao XU
1
;
Minliang CHEN
1
Author Information
1. 解放军总医院第四医学中心烧伤整形医学部，北京 100048
- Publication Type:Journal Article
- Keywords:
Hyaluronic acid;
Vascular complications;
Psychology
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2025;31(4):388-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate changes in psychological status before and after sequential therapy in patients with skin circulatory disorders following hyaluronic acid injection.Methods:A retrospective study was conducted on 17 female patients, with a mean age of 28-54 (39.5±1.2) years, admitted to the Fourth Medical Center of PLA General Hospital from December 2021 to July 2022. Patients received ultrasound-guided percutaneous arterial puncture or digital subtraction angiography (DSA) guided catheter intervention for hyaluronidase injection, alongside corticosteroid pulse therapy, diuretic administration, neurotrophic support, wound protection, and laser therapy. Psychological assessments, including the Minnesota multiphasic personality inventory (MMPI) and symptom check list-90 (SCL-90), were performed at admission and 30-45 days post-discharge. Changes in assessment scores and patient satisfaction were analyzed.Results:Two patients failed to complete all assessments, leaving 15 cases for final analysis. Affected anatomical regions included the nose/perinasal area (13 cases), temporal region (3 cases), lips (3 cases), and forehead (7 cases). MMPI scores for hypochondriasis, depression, hysteria, psychopathic deviation, paranoia, psychasthenia, and hypomania showed statistically significant reductions compared to baseline (all P<0.05). SCL-90 scores for somatization, obsessive-compulsive symptoms, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism, and sleep/appetite disturbances also demonstrated significant decreases (all P<0.05). Among the 15 patients, 7 patients reported being very satisfied, 6 patients were satisfied, and 2 patients were moderately satisfied, with no dissatisfaction reported. Conclusion:Sequential therapy is associated with improved psychological outcomes in patients with skin circulatory disorders secondary to hyaluronic acid injection.
