Current researches and future prospects of imminent fracture risk assessment models for osteoporosis
10.3760/cma.j.cn115530-20250328-00134
- VernacularTitle:骨质疏松患者近期骨折风险评估模型的研究现状与展望
- Author:
Shengliang LIN
1
;
Yuanjing LIAO
1
;
Dehong YANG
1
Author Information
1. 南方医科大学南方医院骨科-脊柱骨科，广州 510515
- Publication Type:Journal Article
- Keywords:
Osteoporosis;
Fractures, bone;
Risk assessment models
- From:
Chinese Journal of Orthopaedic Trauma
2025;27(9):823-828
- CountryChina
- Language:Chinese
-
Abstract:
Osteoporosis is a systemic disease characterized by decreased bone mass and deterioration of bone microstructure, significantly increasing the risk of fragility fractures. With aging global populations, osteoporotic fractures impose a substantial healthcare burden. Strategy of risk-based tiered treatment optimizes cost-effectiveness. Current mainstream tools for fracture risk assessment integrate multiple risk parameters to estimate fracture probability over 5 to 10 years. However, these tools exhibit such limitations as long prediction intervals, insensitivity to temporal dynamics in fracture risk, and difficulties in accurate assessment of short-term (12 to 24 months) fracture risk and treatment response. Imminent fracture risk models address these shortcomings by incorporating time-sensitive indicators such as fractures, fall events, bone mineral density, and imaging findings. They identify the high-risk window for an imminent fracture, enhance precision in recognizing high-risk individuals, and facilitate personalized intervention strategies, thereby offering greater clinical utility. This article reviews the current researches in imminent fracture risk assessment models for osteoporosis and discusses their future developments in association with the recent research findings by our team.
