Study on left atrial remodeling in patients with non-obstructive hypertrophic cardiomyopathy and atrial fibrillation using four-dimensional automatic left atrial quantification technology
10.3760/cma.j.cn131148-20241007-00517
- VernacularTitle:四维自动左心房定量评价对非梗阻性肥厚型心肌病合并心房颤动患者左心房结构和功能
- Author:
Ting WU
1
;
Tianyu HUANG
;
Qingqing ZHAO
;
Manman YANG
;
Cunying CUI
;
Lin LIU
;
Chengzeng WANG
Author Information
1. 郑州大学第一附属医院超声医学科 河南省慢病防治与智慧健康管理重点实验室，郑州 450052
- Publication Type:Journal Article
- Keywords:
Four-dimensional automatic quantification technology;
Hypertrophic cardiomyopathy;
Left atrium;
Atrial fibrillation
- From:
Chinese Journal of Ultrasonography
2025;34(4):311-318
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the left atrial structure and function in patients with non-obstructive hypertrophic cardiomyopathy（NOHCM）and atrial fibrillation（AF）using four-dimensional automatic left atrial quantification（4D Auto LAQ）technology，and to explore the correlation between left atrial remodeling and AF.Methods:Ninety patients with NOHCM treated in the First Affiliated Hospital of Zhengzhou University from May 2023 to September 2024 were prospectively selected and divided into AF group（ n=27）and non-AF group（ n=63）according to whether they had AF. Clinical data of all enrolled patients were collected，and two-dimensional，color Doppler，and tissue Doppler ultrasound parameters were measured. 4D Auto LAQ technology was used to obtain left atrial volume and strain parameters. Inter-group comparison，univariate and multivariate Logistic regression analysis，and repeatability test were used to analyze the data. Results:Compared with non-AF group，left atrial maximum volume index（LAVImax），left atrial minimum volume index（LAVImin）and left atrial pre-systolic volume index（LAVIpreA）were increased in the AF group，but left atrial total ejection fraction（LAEF），left atrial passive ejection fraction（LApEF），left atrial active ejection fraction（LAaEF）and the absolute values of left atrial reservoir longitudinal and circumferential strains（LASr，LASr-c），left atrial conduit longitudinal and circumferential strains（LAScd，LAScd-c）and left atrial contraction longitudinal and circumferential strains（LASct，LASct-c）were decreased（all P<0.05）. Multivariate Logistic regression analysis showed that LAVImin was independently associated with AF（ OR=0.837， P<0.001）. Conclusions:4D Auto LAQ can quantitatively evaluate the left atrial structure and function in patients with NOHCM and AF，and LAVImin is independently associated with the presence of AF.
