Imaging findings of contrast-enhanced ultrasound in diagnosis of solid pseudopapillary tumor of pancreas compared with contrast-enhanced computed tomography
10.3760/cma.j.cn131148-20241024-00545
- VernacularTitle:胰腺实性假乳头状瘤超声造影及增强CT特征的对比研究
- Author:
Zebang YANG
1
;
Wenxin WU
1
;
Xiaoer ZHANG
1
;
Tongyi HUANG
1
;
Lin JIANG
1
;
Jiaqian YAO
1
;
Xiaoyan XIE
1
;
Ming XU
1
Author Information
1. 中山大学附属第一医院超声医学科，广州 510080
- Publication Type:Journal Article
- Keywords:
Contrast-enhanced ultrasound;
Solid pseudopapillary tumor of pancreas;
Contrast-enhanced computed tomography;
Enhancement pattern
- From:
Chinese Journal of Ultrasonography
2025;34(3):216-224
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the diagnostic value of contrast-enhanced ultrasound（CEUS）in solid pseudopapillary tumor of pancreas（SPTP），summarize the CEUS characteristics of SPTP，and to compare its CEUS enhancement with contrast-enhanced computed tomography（CECT）.Methods:In this retrospective study，baseline characteristics，basic ultrasound and CEUS images，CECT images of 70 patients diagnosed as SPTP from January 2009 to August 2023 were collected. Images were analyzed for extraction of key features and diagnostic accuracies of both CEUS and CECT were calculated. The relationships between ultrasound features and lesion size of SPTP were analyzed by Point-Biserial correlation analysis and Student t test. The diagnostic accuracy was compared by Mann-Whitney U test. Results:Iso-enhancement（55.7%，39/70）was commonly appeared in the early phase of CEUS for SPTP，while hypo-enhancement（74.3%，52/70）was the most common in the late phase. And the most common enhancement pattern was iso-hypo enhancement（41.4%，29/70）. Lesion membrane enhancement（47.1%，33/70），intralesional compartmentalization（28.6%，20/70），and intralesional vessels（25.7%，18/70）were the 3 typical signs found in CEUS for SPTP，which were correlated with lesion size（ P＜0.001）. Differences were found between the enhancement pattern of SPTP in CEUS and CECT，in which the most common enhancement patterns were hypo-hypo enhancement（41.4%，24/58）and iso-iso enhancement（29.3%，17/58）along with progressive enhancement. The diagnostic accuracies of CEUS and CECT were 71.4% and 74.1% respectively without statistically significant difference（ P=0.733）. Conclusions:CEUS shows high application value in the diagnosis of SPTP，and the accuracy of CEUS is comparable to that of CECT.
