Using compound muscle action potential scanning to estimate motor unit numbers and explore their normal reference values
10.3760/cma.j.cn113694-20241213-00800
- VernacularTitle:采用复合肌肉动作电位扫描进行运动单位数目估计及其正常值探讨
- Author:
Ting QIU
1
;
Xingyu CHEN
;
Zhenshuo ZHUANG
;
Zhangyu ZOU
Author Information
1. 厦门大学附属中山医院神经内科，厦门361004
- Publication Type:Journal Article
- Keywords:
Action potentials;
Reference values;
Motor unit number estimation;
Abductor pollicis brevis muscle;
Abductor digiti minimi muscle
- From:
Chinese Journal of Neurology
2025;58(4):366-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the motor unit number estimation (MUNE) by compound muscle action potential scanning (MScan) in healthy people and establish its normal values of electrophysiological lab.Methods:One hundred and twenty-six healthy subjects admitted to Electrophysiological Lab of Zhongshan Hospital, Xiamen University from January 2023 to March 2024 were enrolled. The ulnar nerve and the median nerve were stimulated at the wrist and a compound muscle action potential (CMAP) scan from the abductor digiti minimi muscle and the abductor pollicis brevis muscle was recorded, respectively. CMAP and MUNE were obtained. The differences in the MScan MUNE from the abductor pollicis brevis muscle and abductor digiti minimi muscle of healthy subjects of different genders and age groups were analyzed.Results:The values of the Mscan MUNE from the abductor pollicis brevis muscle and abductor digiti minimi muscle of 126 healthy subjects were 115.61±29.96 and 124.17±32.80, respectively. Spearman correlation analysis showed that Mscan MUNE in healthy subjects tended to increase with the increase of CMAP amplitude (abductor pollicis brevis muscle R2=0.190, P<0.001; abductor digiti minimi muscle R2=0.065, P=0.001). There were no significant differences in the MScan MUNE of different gender groups and different age groups (all P>0.05). Conclusions:The differences in age and gender of the subjects had no significant effect on the values of the MScan MUNE. The normal values of the MScan MUNE in the abductor pollicis brevis muscle and abductor digiti minimi muscle were 115.61±29.96 and 124.17±32.80.
