Construction of laboratory biosafety evaluation index system for emergency public health events in medical institutions from the perspective of integrating routine and emergency measures
10.3760/cma.j.cn113565-20241012-00270
- VernacularTitle:平急结合视角下医疗机构重大突发公共卫生事件实验室生物安全评估指标体系构建
- Author:
Di ZHANG
1
;
Fangchao LIU
1
;
Fengling MI
1
;
Zihui LI
1
;
Hairong HUANG
1
;
Liping PAN
1
;
Guangli SHI
1
;
Guanglu JIANG
1
;
Junhua PAN
1
Author Information
1. 首都医科大学附属北京胸科医院，北京 101149
- Publication Type:Journal Article
- Keywords:
Combination of calmness and urgency;
Public health;
Biosafety;
Indicator system;
Evaluation system
- From:
Chinese Journal of Medical Science Research Management
2025;38(3):182-190
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To construct a biosafety evaluation index system for major emergency public health events in medical institutions.Methods:Based on previous laboratory biosafety evaluation work, relevant regulations and standards on biosafety in China were collected through literature research and expert consultations. Candidate indicators for constructing the biosafety evaluation system for major emergency public health events in medical institutions were selected, and a framework was established. Two rounds of expert questionnaires were conducted to determine the content of the index system based on experts′ evaluation, and each indicator′s relevance and importance were scored. Finally, two rounds of Delphi consultations were carried out, and the Analytic Hierarchy Process (AHP) was applied to calculate the weights of indicators.Results:The response rates for the total four rounds of questionnaire surveys were all 100%. The first two rounds focused on determining the framework, while the latter two focused on determining the weights for each indicator. The authority coefficients of the expert consultations for the two rounds of weights were 0.65 and 0.70, respectively, indicating the reliability of the research results. In the final round of survey, the Kendall′s coefficients of concordance at each level were all greater than 0.1. Through statistical testing, the P-values were all less than 0.05, indicating good coordination of expert opinions. Ultimately, we established an operational biosafety evaluation system for major emergency public health events in medical institutions, consisting of 4 primary indicators, 26 secondary indicators, and 119 tertiary indicators, with additional deduction items, bonus items, unacceptable items, and monitoring indicators.Conclusions:Based on scientific theory, a biosafety evaluation system for major emergency public health events in medical institutions was constructed, achieving the integration of routine and emergency measures. This system can be used for self-assessment of laboratory biosafety during emergency public health events, addressing the lack of unified standards in biosafety evaluation. Through regular self-assessment, it can enhance the level of biosafety management in medical institution laboratories, to realize the value of application and dissemination.
