The analysis of risk factors for death in patients with acute kidney injury undergoing continuous renal replacement therapy after cardiac surgery
10.3760/cma.j.cn112434-20240516-00136
- VernacularTitle:心脏术后急性肾损伤患者行连续性肾脏替代治疗的死亡危险因素分析
- Author:
Minghui LI
1
;
Wenwen XU
;
Min FENG
;
Yanna DOU
Author Information
1. 郑州大学第一附属医院重症医学科，郑州 450052
- Publication Type:Journal Article
- Keywords:
Cardiac Surgery;
Acute kidney injury;
Continuous renal replacement therapy;
Mortality risk
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2025;41(2):82-90
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study intends to analyze the differences of indexes between the death group and the survival group of CSA-AKI patients undergoing CRRT before, during, and after heart surgery, and at the beginning and the end of CRRT, and to study the risk factors affecting the death of patients, so as to provide guidance for improving the prognosis.Methods:From January 2020 to October 2022, a total of 101 patients (59 in the mortality group and 42 in the survival group) were admitted to the Department of Cardiac Surgery at the First Affiliated Hospital of Zhengzhou University for cardiac surgery complicated by acute kidney injury necessitating postoperative continuous renal replacement therapy (CRRT). A retrospective analysis of clinical data was conducted to ascertain the risk factors influencing the 30-day mortality rate.Results:The postoperative complications of the two groups showed that the mortality group had a large proportion of MODS and LCOS ( P<0.05). Multivariate regression analysis showed that intraoperative mean arterial depression, high SOFA score at the beginning of CRRT, high APACHE Ⅱ score at the beginning of CRRT, and low platelet at the end of CRRT were independent risk factors for death( P<0.05). ROC curve analysis shows that SOFA score and APACHE Ⅱ score at the beginning of CRRT have predictive value for the 30-day death risk of CSA-AKI patients receiving CRRT. Conclusion:Low intraoperative MAP, high SOFA and APACHE Ⅱ scores at the beginning of CRRT, and low platelets at the end of CRRT were independent risk factors for 30-day mortality risk in patients with CSA-AKI undergoing CRRT.
