A case diagnosed as highly virulent and highly resistant Campylobacter jejuni ST7268 bloodstream infection
10.3760/cma.j.cn114452-20240403-00180
- VernacularTitle:高毒力高耐药空肠弯曲菌ST7268血流感染确诊1例
- Author:
Fang WANG
1
;
Fen GAO
;
Yue LIU
;
Yanan WANG
;
Xuebin XU
Author Information
1. 滕州市中心人民医院检验科，山东滕州277500
- Publication Type:Journal Article
- Keywords:
Campylobacter jejuni;
Invasive;
Genome;
Virulence factor;
Multidrug resistant
- From:
Chinese Journal of Laboratory Medicine
2025;48(1):149-152
- CountryChina
- Language:Chinese
-
Abstract:
A 51-year-old female patient was admitted to the hospital due to abdominal pain, vomiting, and fever lasting for one day. The clinical diagnosis was acute pelvic inflammatory disease and adenomyosis. Empirical treatment with cefoperazone/sulbactam sodium was given. Six days later, the blood culture reported Campylobacter jejuni ( C. jejuni), and nine days later, the patient was discharged with negative blood culture. The strain was identified as C. jejuni by morphology and matrix-assisted laser de-sorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). Whole-genome sequencing predicted that the multi-locus sequence type was ST7268 (ST464 complex), which was a new invasive clone of foodborne C. jejuni with typical molecular characteristics of high vitality, high virulence and high resistance.
