Diagnosis and treatment strategies of autoimmune hepatitis and future challenges
10.3760/cma.j.cn501113-20250508-00179
- VernacularTitle:自身免疫性肝炎的诊治策略与未来挑战
- Author:
Tianyu MAO
1
;
Xiao XIAO
1
;
Xiong MA
1
Author Information
1. 上海交通大学医学院附属仁济医院消化内科 上海市消化疾病研究所,上海 200001
- Publication Type:Journal Article
- Keywords:
Autoimmune hepatitis;
Diagnostic criteria;
Therapeutic;
Quality of life
- From:
Chinese Journal of Hepatology
2025;33(7):617-621
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune hepatitis (AIH) is a kind of immune-mediated chronic liver disease, and its specific pathogenesis has not yet been fully elucidated. In recent years, the International Autoimmune Hepatitis Expert Group has revised histology and autoantibody evaluation criteria for diagnosing AIH and has clarified the definition of treatment response. The current standard treatment regimen is still glucocorticoids and azathioprine, but novel biological agents offer new therapeutic options for patients with refractory AIH. This article reviews the new progress in the diagnosis and treatment of AIH and explores the current challenges and future research directions.