Urinary continence and short-term oncologic efficacy of total prostatic urethral preservation(TPUP)technique in laparoscopic radical prostatectomy
10.3760/cma.j.cn112330-20241216-00558
- VernacularTitle:腹腔镜根治性前列腺切除术中全前列腺尿道保留技术的短期肿瘤学疗效和对术后尿控的影响
- Author:
Xiangrong YING
1
;
Ke GAO
1
;
Zibin XU
1
;
Haojie ZHANG
1
;
Chong SHEN
1
;
Yu REN
1
;
Zhengang LUO
1
;
Gangfeng WU
1
Author Information
1. 绍兴市人民医院泌尿外科（结石），绍兴 312000
- Publication Type:Journal Article
- Keywords:
Prostate neoplasms;
Laparoscopic radical prostatectomy;
Total prostatic urethral preservation;
Urinary incontinence
- From:
Chinese Journal of Urology
2025;46(10):764-768
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the short-term oncological efficacy of the total prostatic urethra preservation（TPUP）technique in laparoscopic radical prostatectomy and its impact on postoperative urinary continence rate.Methods:The clinical data of 17 prostate cancer patients admitted to Shaoxing People’s Hospital from July 2023 to July 2024 were retrospectively analyzed. The age was（70.5 ± 6.5）years，the body mass index was（23.6 ± 2.5）kg/m 2，and the prostate-specific antigen（PSA）level was（7.845 ± 3.929）ng/ml. The preoperative biopsy pathological Gleason score were 6 in 8 cases，and 7 in 9 cases. All patients underwent laparoscopic radical prostatectomy，and the TPUP technique was used during the operation. The integrity of the preserved urethra was improved by preserving the prostatic surgical capsule closely attached to the corpus spongiosum of the urethra. During the operation，the urethra was completely preserved in 2 cases，nearly completely preserved in 14 cases，and partially preserved in 1 case. The recovery of urinary continence on the day of catheter removal and at 1 and 3 months after the operation was recorded. Recovery of urinary continence was defined as pad within 24 hours. PSA was re - examined at 6 weeks and 3 months after the operation. Results:All 17 operations in this study were successfully completed. The operation time was（143.6 ± 31.6）minutes，and the intraoperative blood loss was 50.0（20.0，50.0）ml. None of the cases was converted to open surgery，and no Clavien - Dindo grade ≥ 2 complications such as blood transfusion or intestinal injury occurred during the peri-operative period. The PSA levels at 6 weeks and 3 months after the operation were 0.054（0.008，0.215）ng/ml and 0.008（0.005，0.037）ng/ml，respectively. The indwelling catheter time after the operation was（13.4 ± 2.1）days. The number of cases with recovered urinary continence on the day of catheter removal and at 1 and 3 months after the operation was 10，15，and 17，respectively.Conclusions:The TPUP technique in laparoscopic radical prostatectomy leads to good recovery of postoperative urinary continence，and there is a slowly PSA decrease in the short term.
