Overview of Research on group C Rotavirus gastroenteritis
10.3760/cma.j.cn112866-20250613-00123
- VernacularTitle:C组轮状病毒胃肠炎研究概况
- Author:
Ke LI
1
;
Xiao WEI
;
Jinsong LI
;
Zhaojun DUAN
Author Information
1. 中国疾病预防控制中心病毒病预防控制所传染病溯源预警与智能决策全国重点实验室 国家卫生健康委医学病毒和病毒病重点实验室，北京 102206
- Publication Type:Journal Article
- Keywords:
Group C rotavirus;
Rotavirus gastroenteritis;
Virology;
Epidemiology;
Prevention and control
- From:
Chinese Journal of Experimental and Clinical Virology
2025;39(4):526-532
- CountryChina
- Language:Chinese
-
Abstract:
Group C rotavirus（RVC）is one of the important etiological agents responsible for human rotavirus gastroenteritis（RVGE）. Although its overall detection rate has shown a declining trend in recent years，sporadic outbreaks continue to be reported，highlighting its potential public health threat. RVC infections predominantly occur in preschool children，adolescents，and adults，typically presenting with mild to moderate diarrhea. While most cases are sporadic，cluster outbreaks can also occur. At present，fundamental research on RVC remains limited，particularly regarding its transmission and pathogenesis. Nevertheless，emerging evidence suggests that interspecies transmission may represent a key route of human infection. This review provides a comprehensive overview of current research on RVC-associated gastroenteritis，with a particular focus on its virological characteristics，epidemiological patterns，clinical manifestations，and preventive and control strategies. It aims to offer a theoretical foundation and practical reference for future studies and public health interventions targeting RVC.
