Pathogen investigation of acute respiratory tract infection cases in Yucheng from March to June 2023
10.3760/cma.j.cn112866-20250108-00005
- VernacularTitle:2023年3～6月虞城急性呼吸道感染病例的病原体调查
- Author:
Qi WEN
1
;
Huarong YANG
;
Qin LUO
;
Ze CHEN
;
Qiangqiang SHI
;
Haijun DU
;
Chen GAO
;
Guoyong MEI
;
Jun HAN
;
Qinqin SONG
;
Shuying LI
Author Information
1. 华北理工大学基础医学院 河北省慢性疾病基础医学重点实验室，唐山 063210
- Publication Type:Journal Article
- Keywords:
Acute respiratory tract infection;
Respiratory pathogens;
Epidemiology
- From:
Chinese Journal of Experimental and Clinical Virology
2025;39(2):189-194
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Analysis of the composition of pathogen spectrum and prevalence characteristics in throat swabs of patients with acute respiratory infections (ARI) in Yucheng city, Henan province, from March to June 2023.Methods:After 1 153 throat swabs were collected from ARI patients in Yucheng, 18 respiratory pathogens were tested using a real-time fluorescence quantitative polymerase chain reaction (qPCR) method. The characterization of pathogens spectrum was analyzed.Results:A total of 1 153 throat swabs from ARI patients were collected from March to June 2023 in Yucheng, including 171 outpatients and 982 hospitalized patients. A total of 244 positive samples for common respiratory pathogens were detected (at least one pathogen per sample was detected). The total detection rate of respiratory pathogens was 21.16%, and the top three detection rates were, in descending order, human bocavirus (HBoV), enterovirus (EV), and human parainfluenza virus (HPIV). The main detection month for pathogens was May, with a detection rate of 42.3% (60/142). The main respiratory pathogens detected are HBoV, EV, and HPIV. The detection rate of the age group under 1 year old was the highest, at 25.1% (49/195), mainly consisting of HBoV, respiratory syncytial virus (RSV), and HPIV. The main clinical manifestations of respiratory pathogen-positive patients were fever and cough, and the clinical diagnosis was mainly lower respiratory tract infection, all of which were hospitalized patients.Conclusions:The respiratory pathogens in ARI patients were mainly HBoV, EV, and HPIV from March to June, 2023 in Yucheng. The peak of the epidemic was in May, mainly infecting children under 5 years of age.
