Value of pulmonary ultrasound B-line score,LVEF,IGFBP7 and NT-proBNP in differentiating cardiogenic acute dyspnea
10.3969/j.issn.1673-9701.2025.25.005
- VernacularTitle:肺部超声B线评分、LVEF及IGFBP7、NT-proBNP鉴别心源性急性呼吸困难的价值
- Author:
Feilong XIAO
1
;
Jianghua CHENG
1
;
Yingwei DING
1
;
Yun MAO
1
Author Information
1. 金华市中心医院急诊科,浙江金华 321000
- Publication Type:Journal Article
- Keywords:
Dyspnea;
Cardiogenic;
Pulmonary ultrasound B-line score;
Left ventricular ejection fraction;
Insulin-like growth factor binding protein-7;
N-terminal pro-brain natriuretic peptide
- From:
China Modern Doctor
2025;63(25):19-23
- CountryChina
- Language:Chinese
-
Abstract:
Objective Exploring the clinical value of pulmonary ultrasound B-line score,left ventricular ejection fraction(LVEF),insulin-like growth factor binding protein-7(IGFBP7),and N-terminal pro-brain natriuretic peptide(NT-proBNP)levels in diagnosing cardiogenic acute dyspnea.Methods A retrospective analysis was conducted on the clinical data of 80 patients with acute dyspnea diagnosed and treated at Jinhua Municipal Central Hospital from February 2021 to February 2024.According to the discharge diagnosis of patients,they were divided into cardiogenic group(cardiogenic acute dyspnea,50 cases)and non-cardiogenic group(non-cardiogenic acute dyspnea,30 cases).The pulmonary ultrasound B-line score,LVEF,IGFBP7 and NT-proBNP levels of two groups of patients were compared,their correlations were analyzed,and the receiver operating characteristic(ROC)curve was drawn to evaluate the diagnostic value of each index for cardiogenic acute dyspnea.Results There were no statistically significant differences in the clinical baseline data such as age,gender,body mass index,proportion of atrial fibrillation,urea nitrogen,serum creatinine,systolic blood pressure,arterial partial pressure of oxygen,heart rate and blood oxygen saturation between two groups of patients(P＞0.05).The pulmonary ultrasound B-line score,the levels of IGFBP7 and NT-proBNP in cardiogenic group were significantly higher than those in non-cardiogenic group,and the LVEF was significantly lower than that in non-cardiogenic group(P＜0.05).Pearson correlation analysis showed that the pulmonary ultrasound B-line score was positively correlated with both IGFBP7 and NT-proBNP(P＜0.05),with no significant correlation with LVEF(P＞0.05).The results of ROC curve showed that the pulmonary ultrasound B-line score,LVEF,IGFBP7 and NT-proBNP all had high diagnostic value for cardiogenic acute dyspnea,and the area under the curve were 0.917,0.855,0.946 and 0.925,respectively.Conclusion The pulmonary ultrasound B-line score,LVEF,IGFBP7,and NT-proBNP levels have high diagnostic value for cardiogenic acute dyspnea and are worthy of clinical promotion and application.
