Low contrast dose and low flow rate one-stop craniocervical CT angiography-cerebral CT perfusion for detecting carotid atherosclerosis
10.13929/j.issn.1003-3289.2025.07.023
- VernacularTitle:低对比剂低流率一站式头颈CT血管造影-脑CT灌注成像用于检出颈动脉粥样硬化
- Author:
Yuanyuan CUI
1
;
Rongrong FAN
;
Qinling JIANG
;
Xiaolei SHI
;
An SUN
;
Chenshi ZHANG
;
Weimin YUAN
;
Shiyuan LIU
;
Yi XIAO
Author Information
1. 海军军医大学第二附属医院放射诊断科,上海 200003
- Publication Type:Journal Article
- Keywords:
atherosclerosis;
carotid arteries;
tomography,X-ray computed;
contrast medium;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2025;41(7):1144-1149
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of low contrast dose and low flow rate one-stop craniocervical CT angiography(CT A)-cerebral CT perfusion(CTP)for detecting carotid atherosclerosis(CAS).Methods Totally 117 CAS patients were prospectively enrolled and divided into group A(n=19),B(n=52),C(n=46),and low contrast dose and low flow rate one-stop craniocervical CTA-brain CTP scanning,low contrast dose and low flow rate craniocervical CT A scanning,as well as conventional craniocervical CT A scanning were performed,respectively.Virtual monoenergetic images(VMI)of 40,50 and 60 keV were reconstructed in group A and B.The subjective and objective evaluations of image quality were compared among 3 groups.Results Subjective scores of image quality and diagnostic confidence of 40 and 50 keV VMI,and the diagnostic confidence of 60 keV VMI in group A and B were not significant different compared with those in group C(all P＞0.05).Signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)of each segment of craniocervical blood vessels at 40 and 50 keV VMI in group A and B were all higher than those in group C(all P＜0.05).CNR of cavernous sinus segment of internal carotid artery(C5 segment),horizontal segment of middle cerebral artery(MCA)(A1 segment),lateral sulcus segment of MCA(M2 segment)and basilar artery(BA)segment in group A at 60 keV VMI were all higher than those in group C(all P＜0.05).SNR of C5 segment,A1 segment and BA segment,as well as CNR of BA segment of 60 keV VMI in group B were all higher than those in group C(all P＜0.05).Conclusion Low contrast dose and low flow rate one-stop craniocervical was feasible for detecting CAS.
