Relationship of RDW and blood lipid metabolism indicators with carotid atherosclerotic plaque stability in elderly patients with ACI
10.3969/j.issn.1009-0126.2025.09.021
- VernacularTitle:老年急性脑梗死患者红细胞分布宽度和血脂代谢指标与颈动脉粥样硬化斑块稳定性的关系
- Author:
Yong NI
1
;
Xiang WU
;
Xianghai KONG
;
Meina GONG
;
Tingting LIU
;
Dandan CHEN
Author Information
1. 241000 芜湖市中医医院检验科
- Publication Type:Journal Article
- Keywords:
brain infarction;
erythrocyte volume;
dyslipidemias;
plaque,atherosclerotic
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(9):1229-1232
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the relationship of red blood cell distribution width(RDW)and blood lipid metabolism indicators with carotid atherosclerotic plaque stability in elderly patients with acute cerebral infarction(ACI).Methods A total of 110 elderly ACI patients admitted in our hospital from March 2021 to November 2024 were retrospectively recruited,and according to their carotid plaque characteristics,they were divided into stable plaque group(48 cases)and unstable plaque group(62 cases).The RDW,and levels of TC,TG,HDLC,LDL-C and homocysteine(Hcy)were detected.Results The unstable plaque group had significantly higher levels of RDW,TC,TG,LDL-C and Hcy,but lower HDL-C level than the stable plaque group(P＜0.01).RDW,TC,TG,HDL-C,LDL-C and Hcy were the influencing factors of carotid atherosclerotic plaque stability in elderly ACI patients(P＜0.05,P＜0.01).ROC curve analysis suggested that the AUC value of combined detection of RDW,TC,TG,HDL-C,LDL-C and Hcy in evaluating the stability of carotid atherosclerotic plaque was 0.940(95％CI:0.898～0.983),and the combination had bet-ter efficiency than single indicator detection(P＜0.05).Conclusion RDW and blood lipid metabo-lism indicators are associated with the stability of carotid atherosclerotic plaque in elderly ACI patients,and they can be used as biochemical evaluation indicators for the stability.
