Risk factors for atrial high-rate episodes in elderly patients after dual-chamber pacemaker implantation
10.3969/j.issn.1009-0126.2025.09.016
- VernacularTitle:双腔起搏器置入术后老年患者发生心房高频事件的危险因素分析
- Author:
Wenkun CHENG
1
;
Jianhua LI
1
;
Lu WANG
1
;
Haijun WANG
1
;
Yan GUO
1
Author Information
1. 100853 北京,解放军总医院第二医学中心心血管内科国家老年疾病临床医学研究中心
- Publication Type:Journal Article
- Keywords:
pacemaker,artificial;
atrial fibrillation;
risk factor;
atrial high-rate episodes
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(9):1208-1211
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for AHRE after dual-chamber pacemaker im-plantation in elderly patients without history of atrial fibrillation.Methods A retrospective analy-sis was conducted on 159 elderly patients receiving implantation of cardiac dual-chamber pace-makers in the Chinese PLA General Hospital from January 2018 to December 2020.Based on oc-currence of AHRE or not,they were divided into an AHRE group(73 cases)and a non-AHRE group(86 cases).Cox proportional hazards analysis were performed to analyze the survival and risk factors of AHRE.Results Heart failure(HR=2.134,95%CI:1.212-3.758,P=0.009),his-tory of stroke/transient ischemic attack/thromboembolism(HR=2.378,95%CI:1.293-4.375,P=0.005),atrial sensing amplitude<2.0 mV(HR=2.258,95%CI:1.307-3.900,P=0.004),NT-proBNP>900 ng/L(HR=1.740,95%CI:1.024-2.955,P=0.040),and eGFR<60 ml/(min·1.73 m2)(HR=2.118,95%CI:1.227-3.655,P=0.007)were independent risk factors for new-onset AHRE in elderly patients after dual-chamber pacemaker implantation.Conclusion For elderly patients without history of atrial fibrillation after cardiac dual-chamber pacemaker implan-tations,the occurrence of AHRE is significantly associated with multiple risk factors such as heart failure,history of stroke/transient ischemic attack/thromboembolism,eGFR<60 ml/(min·1.73 m2),atrial sensing amplitude<2.0 mV,and NT-proBNP>900 ng/L.