Epidemiological characteristics and spatiotemporal clustering analysis of Japanese encephalitis in Yunnan province from 2000 to 2023
10.3760/cma.j.cn112866-20240928-00146
- VernacularTitle:2000—2023年云南省流行性乙型脑炎流行特征及时空聚集分析
- Author:
Shuzhen DENG
1
;
Cong HUA
;
Shilian WANG
;
Wenwen LI
;
Hailin ZHANG
Author Information
1. 云南省疾病预防控制中心，昆明 650022
- Publication Type:Journal Article
- Keywords:
Japanese encephalitis;
Epidemiological characteristics;
Spatiotemporal aggregation
- From:
Chinese Journal of Experimental and Clinical Virology
2024;38(6):642-648
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the epidemiological characteristics of Japanese encephalitis (JE) in Yunnan province, China from 2000 to 2023, and to provide scientific basis for prevention and control work.Methods:Descriptive epidemiological method were used for epidemiological feature analysis. Excel 2019 and ArcGIS 10.8.2 software were used to establish case databases and map drawings, Joinpoint 4.9.1 software was used to conduct time trend analysis, and ArcGIS 10.8.2 software was used to construct a geographic information database and conduct spatial autocorrelation analysis. SaTScan 10.1.2 software was used for spatiotemporal scanning analysis.Results:A total of 7 006 JE cases and 342 deaths were reported in Yunnan province from 2000 to 2023, with an average annual incidence of 0.58/100 000 (0.03/100 000-1.69/100 000) and a fatality rate of 4.88%, both of which showed a decreasing trend. JE cases have been reported in 129 counties in 16 prefectures of the province, and the average annual incidence rate in prefecture was 0.09/100 000-1.96/100 000. Xishuangbanna, Dehong, Zhaotong, Baoshan, Pu′er, Wenshan and Chuxiong prefectures were highly prevalent areas. Spatial-temporal scanning analysis found that 33 counties in 6 prefectures in the China-Myanmar and China-Laos border areas in southwest Yunnan constitute the first-class cluster area, and 9 counties in Zhaotong prefecture in northeastern Yunnan constitute the second-class cluster area. JE cases occured in every month of the year, with the main epidemic period from May to October. The ratio of male to female cases was 1.54∶1, the proportion of the age group <15 years was 68.49%, and the age group ≥15 years was 31.51%. The proportion of scattered children and preschool children was 38.54%, with students accounting for 33.19% and farmers accounting for 21.18%.Conclusions:JE was widely distributed in Yunnan province, with high-incidence areas mainly concentrated in southwestern and northeastern Yunnan. The incidence rate among children was high, and the number of cases among adults and farmers has increased significantly. It is still necessary to strengthen the prevention and control of JE in high-risk areas, especially in rural areas, and fully implement the children′s JE immunization program and adult JE prevention measures.
