Examination of antibacterials in clinical use
10.3760/j.issn.1008-5734.2000.03.005
- VernacularTitle:抗菌药物临床应用分析
- Author:
Yueling LI
1
;
Zuojun HUANG
1
;
Yuanshan WU
1
;
Qikun ZHENG
1
Author Information
1. 暨南大学第四附属医院,广东广州,510220
- Publication Type:Journal Article
- Keywords:
antibacterials;
clinical use;
analysis
- From:
Adverse Drug Reactions Journal
2000;2(3):159-164
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To check if antibacterials were rational in clinical use.Methods:143 inpatients between June and December 1998 were enrolled for retrospective analysis of drug administration.Results:132 cases took an tibacterial drugs accounting for 92.3%,among them 69 cases (52.3%) for treatment and 63 cases (47.7%) for preventive purposes.From the said patients only 16 samples were collected and sent for bacterial culture,its positive rate being 31.5 %.Antibacterials taken covered 43 kinds of 10 categories,altogether 1573 drug-days.The rate of the unreasonable application was 39.4 % (52/132 cases) or 42.5 % (668/1573 drug-days).Medication for wrong indications or for a longer period than neccessity could be the main problem.Conclusion:In order to upgrade the diagnostic and therapeutic level,medical professionals should have knowledge of and be familiar with antibacterials and use them in a reasonable way in combination with bacterial culture and drug sensitivity test,if possible.