Flexible subtraction CE-Boost technique combined with low dosage contrast agents for CT pulmonary angiography
10.13929/j.issn.1003-3289.2025.07.024
- VernacularTitle:柔性减影CE-Boost技术联合低对比剂用量用于CT肺动脉血管造影
- Author:
Weijian XU
1
;
Zhenghong BI
;
Yijing GUO
;
Leilei SHEN
;
Jinjuan LU
;
Zicheng ZHAO
;
Mengsu ZENG
;
Mingliang WANG
Author Information
1. 上海市老年医学中心复旦大学附属中山医院闵行院区放射诊断科,上海 201104
- Publication Type:Journal Article
- Keywords:
pulmonary artery;
angiography;
flexible subtraction CE-Boost;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2025;41(7):1150-1153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of flexible subtraction CE-Boost technique combined with low dosage contrast agents for CT pulmonary angiography(CTPA).Methods A total of 68 patients who would undergo CTPA examination due to suspected pulmonary embolism(PE)were prospectively enrolled and randomly divided into study group(n=34)and control group(n=34)using block randomization method.After injecting 25 ml contrast agents at a flow rate of 2.5 ml/s in study group or 50 ml contrast agents at a flow rate of 3.5 ml/s in control group,CTPA scanning were performed with identical parameters.For images in study group,hybrid iterative reconstruction was performed,followed by flexible subtraction CE-Boost post-processing to obtain CE-Boost CTPA.For images in control group,conventional CTPA was obtained with hybrid iterative reconstruction.Subjective and objective evaluations of image quality were compared between groups.Taken the final clinical diagnosis as standard,the accuracy rate of diagnosing PE were compared between groups.Results There were 7 cases of pulmonary artery main trunk PE and 15 cases of pulmonary lobe-level PE in study group,while in control group there were 8 cases and 17 cases.No statistical difference of subjective scores of CTPA was found between groups(P＞0.05).CT values of the main pulmonary artery,bilateral pulmonary artery trunks and lower lobes of both lungs,signal-to-noise ratio or contrast-to-noise ratio in CTPA were not significantly different between groups(all P＞0.05),while no significant difference of the accuracy rate of CTPA for diagnosing PE of pulmonary artery main trunk(100％[7/7]vs.100％[8/8])nor pulmonary lobe-level PE(86.67％[13/15]vs.88.24％[15/17])was detected between groups(all P＞0.05).Conclusion Flexible subtraction CE-Boost technique combined with low dosage contrast agents for CTPA could reduce contrast agent dosage without affecting image quality.
