Association between the metabolic score for visceral fat and sarcopenia in older adults
10.3760/cma.j.issn.0254-9026.2025.11.016
- VernacularTitle:内脏脂肪代谢评分与老年人群肌少症的相关性研究
- Author:
Tong LI
1
;
Meilan LIU
1
;
Qing WANG
1
;
Tianhan SUN
1
;
Jianfu CAO
1
;
Hongyuan CUI
1
Author Information
1. 北京医院普通外科 国家老年医学中心 中国医学科学院老年医学研究院 北京协和医学院，北京 100730
- Publication Type:Journal Article
- Keywords:
Sarcopenia;
Metabolism of fat;
Metabolic score for visceral fat
- From:
Chinese Journal of Geriatrics
2025;44(11):1578-1584
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association between the metabolic score for visceral fat(METS-VF)and sarcopenia in older adults in China.Methods:A retrospective cohort study was conducted.A total of 1 262 participants aged ≥60 years old who did not diagnose with sarcopenia in 2011 and had complete follow-up data in 2015 were selected from the China health and retirement longitudinal survey(CHARLS). Participants were divided into the low METS-VF group (n=621)and the high METS-VF group (n=641), and then the corrleation between METS-VF and sarcopenia was analyzed.Results:The inverse probability of treatment weighting(IPTW)was used to balance all covariates between the low METS-VF group and high METS-VF group.The results showed that 30 participants in the low METS-VF group and 47 participants in the high METS-VF group were diagnosed with sarcopenia, with prevalence rates of 4.83%(30/621)and 7.33%(47/641), respectively.The difference in the prevalence of sarcopenia between the two groups was statistically significant after IPTW ( χ2=3.934, P=0.048, SMD=0.150). Logistic regression analysis showed that, after adjusting for various confounders, high METS-VF was significantly associated with an increased risk of sarcopenia in older adults( OR=2.130, 95% CI: 1.294~3.572, P=0.003). Subgroup analyses further indicated that individuals without cardiovascular disease had a relatively higher risk of sarcopenia( P for interaction=0.032). Conclusions:METS-VF is associated with an increased risk of sarcopenia in older adults in China, and its predictive and diagnostic value warrants further investigation.
