Research progress on Alzheimer′s disease: from early diagnosis to precise intervention
10.3760/cma.j.issn.0254-9026.2025.09.004
- VernacularTitle:阿尔茨海默病研究进展:从早期诊断到精准干预
- Author:
Lin HUANG
1
;
Liang CUI
1
;
Fengfeng PAN
1
;
Qinjie LI
1
;
Heling CHU
1
;
Qihao GUO
1
Author Information
1. 上海交通大学医学院附属第六人民医院老年病科,上海 200233
- Publication Type:Journal Article
- Keywords:
Alzheimer′s disease;
Biomarker;
Target therapy
- From:
Chinese Journal of Geriatrics
2025;44(9):1231-1239
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer′s disease(AD), as a common cognitive impairment disorder in the elderly, has imposed a significant burden on the global public health system.The latest international diagnostic criteria emphasize defining AD from a biological perspective and viewing it as a continuous pathological and physiological change process.This article, guided by the principle of ′early diagnosis-precision intervention′, systematically elaborates on the current research status of AD regarding diagnostic criteria, biomarkers, new drug development, and the establishment of China-specific AD cohorts.It also provides an in-depth outlook on the future research directions and clinical application prospects of AD.