The research progress on the antidiabetic agents related sarcopenia in elderly adults

VernacularTitle:降糖药物与老年肌少症的研究进展
Author: Danqian LI ¹ ; Xiaolin ZHANG ; Shuang ZHOU ; Xinmin LIU
Author Information

1. 北京大学第一医院老年内科，北京　100034
Publication Type:Journal Article
Keywords: Muscle damage; Sarcopenia; Diabetes; Antidiabetic agents; Rational drug use
From: Chinese Journal of Geriatrics 2024;43(12):1643-1650
CountryChina
Language:Chinese
Abstract: Sarcopenia is one of the most common diseases of elderly patients which can affect the physical function and quality of life.Elderly patients not only have high prevalence of type 2 diabetes mellitus, but also have complex polypharmacy.As a result, the risk of antidiabetic agents related skeleton muscle damage and sarcopenia will increase significantly.Therefore, it is extremely important to identify and try to avoid the use of related drugs in the elderly.This article reviewed the types of antidiabetic drugs and mechanism likely leading to sarcopenia, as well as the intervention methods and drug management, to promote the prevention and control of the morbidity of sarcopenia in the elderly and improve the level of rational drug use.