Surveillance and analysis of etiology of viral diarrhea in children under five years old in Baotou city
10.3760/cma.j.cn112309-20241022-00359
- VernacularTitle:包头市5岁以下儿童病毒性腹泻病原学监测分析
- Author:
Xiaojuan CHEN
1
;
Yaoxing LIU
;
Jingxian PENG
;
Yingbo XIE
;
Min GUO
;
Jingyi LU
;
Men WANG
;
Rong JIN
Author Information
1. 包头市疾病预防控制中心微生物检验科，包头 014030
- Publication Type:Journal Article
- Keywords:
Viral diarrhea;
Group A rotavirus;
Norovirus
- From:
Chinese Journal of Microbiology and Immunology
2025;45(6):507-511
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the epidemiological trends of viral diarrhea pathogens in children in Baotou city, and to provide reference for controlling the prevalence of viral diarrhea and guiding the development of regional vaccines.Methods:Fecal samples were collected from children under five years old hospitalized with viral diarrhea at two sentinel hospitals in Baotou from June 2023 to May 2024. Real-time PCR was used to detect group A rotavirus, norovirus, adenovirus, and astrovirus. Statistical analysis was performed using SPSS 20.0 software, with Chi-square tests conducted to assess differences. A P value<0.05 was considered statistically significant. Results:A total of 246 fecal samples were collected, including 153 from males and 93 from females. Among these, 135 samples tested positive, yielding a positivity rate of 54.88% (135/246). There were 82 positive samples from male children and 53 from female children, with no significant difference between genders. Most positive samples (51.85%, 70/135) tested positive for two viruses. Specifically, co-infections of group A rotavirus with norovirus or adenovirus accounted for 98.57% (69/70) of all co-infected cases. Significant differences in detection rates were observed across age groups (χ 2=29.803, P<0.001), with the highest positivity rates in children under one year old and in the 1-year age group. Seasonality, viral diarrhea in Baotou was more prevalent in winter and spring. The G8P[8] genotype of group A rotavirus was the predominant strain. Conclusions:From June 2023 to May 2024, viral diarrhea in hospitalized children under five years old in Baotou is primarily caused by co-infections of group A rotavirus and norovirus, with a higher incidence in preschool-aged children. The G8P[8] genotype of group A rotavirus is the dominant strain. It is recommended to strengthen vaccination and surveillance efforts for viral diarrhea in preschool children, particularly during the winter and spring seasons.
