Related factors of kidney injury in patients with masked hypertension in community
10.3760/cma.j.cn114798-20240517-00464
- VernacularTitle:社区隐蔽性高血压患者肾功能损伤的关联因素分析
- Author:
Zixuan CHEN
1
;
Zuoliang ZHANG
;
Ruibin HU
;
Yanshuang CHEN
;
Dong CHEN
;
Yangmei LI
;
Cuilan SONG
;
Songtao TANG
Author Information
1. 广东省东莞市寮步镇社区卫生服务中心，东莞 523400
- Publication Type:Journal Article
- Keywords:
Hypertension;
Community;
Kidney injury;
Ambulatory blood pressure measurement
- From:
Chinese Journal of General Practitioners
2025;24(1):55-61
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the related factors of kidney injury in patients with masked hypertension (MHT).Methods:This study was a cross-sectional study. A total of 311 MHT patients who visited Dongguan Liaobu Community Health Service from June 1,2022 to June 1, 2023 were enrolled in the study. The complete blood biochemistry, urinary microalbumin and 24-hour urinary protein tests were conducted, and the risk factors of renal injury in MHT patients were analyzed with multivariate logistic regression.Results:The age of the 311 enrolled patients was(48.8±9.2)years, with 192 males(61.7%) There were 73 cases with microalbuminuria (MAU), accounting for 23.47% (73/311); and 28 cases of positive 24-hour urine total protein (24-hour UTP), accounted for 9.00% (28/311). Multivariate logistic regression analysis showed that fasting blood glucose level and mean nocturnal systolic blood pressure were independent risk factors of positive MAU in MHT patients ( OR=1.577, 95% CI: 1.049-2.370, P=0.030; OR=1.024, 95% CI: 1.001-1.047, P=0.038), while older age was a protective factor of MAU ( OR=0.965, 95% CI: 0.935-0.997, P=0.030); mean nocturnal systolic pressure, 24-hour mean systolic pressure and mean diurnal systolic pressure were independent risk factors of positive 24-hour UTP in MHT patients ( OR=1.031,95% CI: 1.000-1.064, P=0.049; OR=1.048,95% CI: 1.008-1.091, P=0.020; OR=1.042,95% CI: 1.003-1.083, P=0.035). Conclusion:Older age, fasting blood glucose, mean nocturnal systolic pressure, 24-hour mean systolic pressure and mean diurnal systolic pressure are associated with the renal injury in MHT patients.
