Advancements in the research of PSMA PET radiomics in prostate cancer

VernacularTitle:PSMA PET影像组学在前列腺癌中的研究进展
Author: Hangxing CHUNYU ¹ ; Jiajia HU ¹ ; Biao LI ¹
Author Information

1. 上海交通大学医学院附属瑞金医院核医学科，上海　200025
Publication Type:Journal Article
Keywords: Prostatic neoplasms; Radiomics; Prostate specific membrane antigen; Positron-emission tomography; Trends
From: Chinese Journal of Nuclear Medicine and Molecular Imaging 2025;45(3):180-184
CountryChina
Language:Chinese
Abstract: Prostate specific membrane antigen (PSMA) PET demonstrates superior accuracy compared to alternative imaging modalities in the diagnosis and treatment of prostate cancer. Nonetheless, subjective interpretation processes still result in false positives and false negatives, leading to erroneous or missed diagnoses, thereby compromising diagnostic efficacy, influencing preoperative grading and risk stratification, and interfering with clinical decision-making. With the rapid advancement of medical imaging technology and artificial intelligence, the role of radiomics is gaining prominence. By leveraging extracted image features and employing quantitative analysis, radiomics based on PSMA PET images holds great potential to enhance the capabilities of diagnosing, grading, quantifying risk, and predicting treatment efficacy in prostate cancer. This article aims to comprehensively review the research progress of PSMA PET radiomics in the clinical diagnosis and treatment of prostate cancer.