Progress in hematopoietic stem cell transplantation for acute myeloid leukemia
10.3760/cma.j.cn121090-20240422-00157
- VernacularTitle:造血干细胞移植在急性髓系白血病中的应用进展
- Author:
Xiaolu ZHU
1
;
Xiaojun HUANG
1
;
Yu WANG
1
Author Information
1. 北京大学人民医院，北京大学血液病研究所，国家血液系统疾病临床医学研究中心，造血干细胞移植治疗血液病北京市重点实验室，北京 100044
- Publication Type:Journal Article
- From:
Chinese Journal of Hematology
2025;46(2):179-185
- CountryChina
- Language:Chinese
-
Abstract:
Acute myeloid leukemia (AML) is a malignant disease of myeloid hematopoietic stem/progenitor cells. Although new drugs have emerged in recent years, the status of hematopoietic stem cell transplantation (HSCT) in AML still remains irreplaceable. This article reviews the adjustment of indications for HSCT in AML, donor selection, and updates of conditioning regimens, new prevention strategies for post-transplant relapse, new targeted drugs, immunotherapy combined with HSCT to improve the prognosis of relapsed and refractory AML, and optimization of transplantation technology for elderly AML.
