Experience summary of coagulation rebalancing therapy for heat stroke-induced coagulopathy

VernacularTitle:应用凝血复衡策略治疗热射病性凝血病的经验总结
Author: Qingwei LIN ¹ ; Xingping DENG ¹ ; Huiqiang LIU ¹ ; Shikai YU ¹ ; Jingchun SONG ¹
Author Information

1. 解放军联勤保障部队第九〇八医院重症医学科/南昌市血栓与止血学重点实验室，南昌　330002
Publication Type:Journal Article
From: Chinese Journal of Hematology 2024;45(S1):97-99
CountryChina
Language:Chinese
Abstract: This case report describes the treatment process of a severe exertional heat stroke-induced coagulopathy in a 20-year-old firefighter. Through a comprehensive treatment strategy of five early and one prevention, including early cooling, early anticoagulation, early coagulation factor supplementation, early anti-inflammation, early blood purification, and prevention of complications, the patient was successfully treated. For the management of heat stroke-induced coagulopathy, based on the coagulation rebalancing strategy-namely anticoagulation combined with goal-directed replacement therapy, along with plasma diafiltration (PDF) treatment-the patient's coagulation function was effectively improved without any bleeding or thrombotic events. The patient's coagulation function returned to normal by day 4 of hospitalization, the tracheal tube was removed on day 6, transferred to the general ward after 11 days, and was discharged after 21 days of rehabilitation.