Diabetic osteoporosis: pathological characteristics, mechanisms and treatment
10.3760/cma.j.issn.0254-9026.2025.07.004
- VernacularTitle:糖尿病性骨质疏松：病理特征、机制和治疗
- Author:
Hao WANG
1
;
Zehao YU
1
;
Xiongfeng TANG
1
;
Yanguo QIN
1
Author Information
1. 吉林大学白求恩第二医院骨科诊疗中心 东北亚老龄主动应对与仿生健康国际合作联合实验室，长春 130041
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Osteoporosis;
Fracture
- From:
Chinese Journal of Geriatrics
2025;44(7):863-869
- CountryChina
- Language:Chinese
-
Abstract:
In the context of an aging population, diabetes has emerged as a significant public health challenge.However, compared to the extensive research on target organs such as the cardiovascular, nervous, and renal systems, the impact of diabetes on the skeletal system has been underestimated.The pathological microenvironment of diabetes and systemic internal environment disorders harm bones by affecting bone density, disrupting bone microstructure, interfering with the bone mineralization process, and reducing the quality of bone collagen, which leads to the development of osteoporosis.Therefore, maintaining bone health should be an important component of comprehensive diabetes management.This review aims to provide an overview of the pathological characteristics, mechanisms, and treatment strategies for osteoporosis in both type 1 and type 2 diabetes, serving as a reference for bone health management in diabetic patients.
