Metabolic disorders and chronic inflammation in osteoarthritis
10.3760/cma.j.issn.0254-9026.2025.07.002
- VernacularTitle:骨关节炎中的代谢紊乱与慢性炎症
- Author:
Tong ZHENG
1
;
Shenghao XU
;
Qibo XU
;
Jianlin XIAO
Author Information
1. 吉林大学中日联谊医院骨科，长春 130033
- Publication Type:Journal Article
- Keywords:
Osteoarthritis;
Metabolic diseases;
Inflammation;
Comorbidity
- From:
Chinese Journal of Geriatrics
2025;44(7):852-857
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of osteoarthritis(OA)has been gradually increasing among China's middle-aged and elderly population, creating a significant burden on healthcare systems.As the co-morbidity patterns of metabolic diseases and OA are increasingly being explored, OA is being redefined as a systemic disease driven by metabolic inflammation.This article focuses on the interactions between metabolic disorders and chronic inflammation in OA, summarizing the regulation of OA through cross-organ interaction mechanisms.The aim is to deepen the understanding of the complex pathophysiological network of OA and to propose potential new therapeutic directions.
