Progress in evaluation of animal disease models based on omics technologies
10.3969/j.issn.1005-4847.2025.06.009
- VernacularTitle:组学技术在疾病动物模型评价中的应用
- Author:
Chao ZHU
1
;
Xing GUO
;
Jine WANG
;
Pingxuan DONG
;
Qianqian GAO
;
Xiaoyue WANG
;
Xiaojie QI
;
Jinju TIAN
Author Information
1. 德州学院药学院,山东德州 253023;新型药用辅料与缓控释制剂山东省工程研究中心,山东德州 253023;德州市组学技术与健康工程研究中心,山东德州 253023
- Publication Type:Journal Article
- Keywords:
omics technologies;
animal disease model;
evaluation standard;
quality control;
biomarkers
- From:
Acta Laboratorium Animalis Scientia Sinica
2025;33(6):866-877
- CountryChina
- Language:Chinese
-
Abstract:
Animal disease models are important biological tools for basic medical research.Establishing an ideal animal model is a critical prerequisite for acquiring reliable experimental data.By enabling molecular-level characterization,omics technologies can enhance the precision of animal model assessments,thereby improving the evaluation criteria.This review summarizes the current applications of omics in evaluating animal disease models,discusses their potential for quality control implementation,and proposes novel frameworks for standardized model validation.
