Evaluation of economic burden of ICU patients due to hospital-associated MDROs infection based on propensity score matching
10.11816/cn.ni.2025-251099
- VernacularTitle:基于倾向指数匹配的ICU多重耐药菌医院感染经济负担评价
- Author:
Mengqi TANG
1
;
Qian YU
;
Zhenping SHA
;
Xiaoqing LIU
;
Furong GENG
;
Shuo LI
;
Zhongming CHEN
Author Information
1. 淄博市中医医院医院感染管理科,山东淄博 255000
- Publication Type:Journal Article
- Keywords:
Propensity score matching;
Multidrug-resistant organism;
Intensive care unit;
Hospital-associated in-fection;
Evaluation of economic burden
- From:
Chinese Journal of Nosocomiology
2025;35(21):3227-3231
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the economic burden of the intensive care unit(ICU)patients due to hospital-associated multidrug-resistant organisms(MDROs)infections based on propensity score matching(PSM)so as to provide evidence-based bases for prevention and control of hospital-associated MDROs infection and improvement of utilization efficiency of medical resources.METHODS A total of 2118 patients who were hospitalized in Zibo Central Hospital from Jan.1,2023 to Dec.31,2024 and conformed to the inclusion and exclusion criteria were re-cruited as the research subjects.The patients with hospital-associated MDROs infections were matched in a 1∶1 ratio by PSM(with the clamp value 0.02).Totally 309 pairs were successfully matched.The length of hospital stay and the costs were observed and compared between the MDROs group and the non-MDROs group.RESULTS The MDROs group was with the length of hospital stay 14.00 days longer than the non-MDROs group after the matching(Z=-5.750,P＜0.001),with the total cost of hospitalization increased by 91,420.84 yuan(Z=-8.271,P＜0.001).With the respect to the medical treatment expenses,the expenses of the MDROs group were higher than those of the non-MDROs group,covering the cost of medical service,therapeutic procedures,nursing,western medicine and TCM,and there were significant differences(P＜0.05).Among the differences in the costs between the two groups,the difference in the cost of western medicine was the most signif-icant(22,182.91 yuan),followed by the cost of clinical laboratory test for diagnosis(19,529.60 yuan)and the cost of therapeutic procedures(16,333.50 yuan).CONCLUSIONS The hospital-associated MDROs infections may lead to the extension of hospital stay length of the ICU patients,which then increases the economic burden.There-fore,it is necessary to strengthen the multidisciplinary collaboration and formulate corresponding measures so as to reduce the risk of such infections among the ICU patients.
