Research Progress of Dihydromyricetin in Pharmacological Effects and Its Preparation
10.19879/j.cnki.1005-5304.202502360
- VernacularTitle:二氢杨梅素药理作用及其制剂研究进展
- Author:
Peng ZHANG
1
;
Kaitong LI
;
Honglan WANG
;
Yuanle SHEN
;
Huini RUAN
;
Zihong LI
;
Jianfang FENG
;
Liuping WANG
Author Information
1. 广西中医药大学药学院,广西 南宁 530200
- Publication Type:Journal Article
- Keywords:
dihydromyricetin;
pharmacological effects;
new preparation;
bioavailability;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(12):192-196,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Dihydromyricetin is a flavonoid mainly found in Ampelopsis grossedentata,which has attracted extensive attention due to its diverse pharmacological activities in recent years.However,its low oral bioavailability limits its clinical application.In this article,the pharmacological effects of dihydromyricetin on antibacterial,antiviral,antitumor,inhibition of neuroinflammation,antioxidant,and hepatorenal protection were reviewed.By summarizing,it can be seen that the pharmacological effects of dihydromyricetin are related to the traditional efficacy of Ampelopsis grossedentata.Scholars have used new preparation technologie to design dosage forms and new drug delivery systems such as liposomes,nanoparticles,microemulsions and nanoemulsions,microcapsules and nanocapsules,which can improve the bioavailability and efficacy of dihydromyricetin.Which can provide reference for the development of new drugs.
