Clinical study on the"Stomach Three Needles"for preventing highly emetogenic chemotherapy-induced acute nausea and vomiting in breast cancer patients
10.3969/j.issn.1673-9701.2025.31.002
- VernacularTitle:"胃三针"防治乳腺癌患者高致吐性化疗所致急性恶心呕吐的临床研究
- Author:
Mengyan LIN
1
;
Wenwu WANG
;
Fangfeng LIN
;
Shuping SHI
;
Jie LIN
;
Biyin CHEN
Author Information
1. 福建中医药大学附属第三人民医院肿瘤科,福建 福州 350108
- Publication Type:Journal Article
- Keywords:
Stomach Three Needles;
Breast cancer;
Highly emetogenic chemotherapy;
Nausea and vomiting
- From:
China Modern Doctor
2025;63(31):8-11,30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effectiveness and safety of the"Stomach Three Needles"in preventing acute chemotherapy-induced nausea and vomiting(CINV)in patients with breast cancer.Methods Seventy patients with breast cancer who received highly emetogenic chemotherapy(HEC)and were admitted to the Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine from January 2023 to May 2025 were selected as research subjects.They were divided into treatment group(35 cases)and control group(35 cases)according to the random number table method.The treatment group received"Stomach Three Needles"combined with triple-drug prophylactic antiemetic therapy,while the patients in control group were given triple-drug prophylactic antiemetic therapy alone.The severity of nausea and vomiting symptoms during the acute phase,functional living index-emesis(FLIE),and adverse reactions between two groups of patients were compared.Results The severity grades of acute-phase nausea and vomiting symptoms in treatment group were all lower than those in control group(P＜0.05).The complete response rate and total effective rate of acute-phase nausea and vomiting in treatment group were significantly higher than those in control group(P＜0.05).The FLIE score of the patients in treatment group was significantly higher than that in control group(P＜0.05).There was no statistically significant difference in the occurrence of adverse reactions such as headache,fatigue,constipation,and abdominal distension between two groups of patients(P＞0.05).Conclusion The"Stomach Three Needles"combined with triple-drug prophylactic antiemetic therapy can effectively reduce the incidence and severity of acute CINV in breast cancer patients,improve their quality of life,and has good safety.It is worthy of clinical promotion.
