Value of geriatric nutritional risk index combined with CHA2DS2-VASc-60 score in predicting short-term prognosis of elderly multimorbid patients with atrial fibrillation
10.3969/j.issn.1009-0126.2025.11.009
- VernacularTitle:老年营养风险指数联合CHA2DS2-VASc-60评分预测老年心房颤动共病患者短期预后的价值
- Author:
Xiuli ZHANG
1
;
Xinhong WANG
;
Haijuan CHENG
;
Jianjun FENG
Author Information
1. 西安交通大学第二附属医院老年综合内科,西安 710004
- Publication Type:Journal Article
- Keywords:
atrial fibrillation;
multiple chronic conditions;
albumins;
malnutrition
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(11):1484-1488
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of geriatric nutritional risk index(GNRI)combined with CHA2DS2-VASc-60 score for short-term prognosis of elderly multimorbid patients with atrial fibrillation.Methods A total of 220 elderly multimorbid patients with non-valvular atrial fibrillation admitted to our hospital from May 2020 to December 2022 were recruited.Clinical data were collected,and GNRI and CHA2DS2-VASc-60 score were calculated.With 98 as a cut-off value of GNRI,the patients were divided into normal nutritional group(109 cases)and nutritional risk group(GNRI ≤ 98,111 cases).Clinical characteristics were compared between the two groups.Multivariate logistic regression analysis was used to identify the influencing factors for compound events in elderly multimorbid patients with atrial fibrillation.Variance inflation factor was adopted for collinearity diagnosis.ROC curve was plotted to evaluate the prognostic value of GNRI,CHA2DS2-VASc-60 score and their combination.Results Compared with the normal nutritional group,the nutritional risk group had significantly advanced age,higher CHA2DS2-VASc-60 score,and larger proportion of concomitant chronic heart failure(P＜0.05).Age(OR=1.228,95％CI:1.112～1.357),GNRI(OR=0.693,95％CI:0.494～0.997)and CHA2DS2-VASc-60 score(OR=1.488,95％CI:1.008～2.194)were influencing factors for the occurrence of complex events(P＜0.05,P＜0.01).The AUC value of GNRI,CHA2DS2-VASc-60 score,and their combination in predicting complex events at the end of 6 months was 0.665(95％CI:0.539～0.791),0.689(95％CI:0.578～0.801),and 0.749(95％CI:0.653～0.844),respectively(P＜0.05).Conclusion Age,GNRI,and CHA2DS2-VASc-60 score are influencing factors for the occurrence of complex events in elderly multimorbid patients with atrial fibrillation.The combination of GNRI and CHA2DS2-VASc-60 score has predictive value for the short-term prognosis of the patients.
