Potential application value of Cistanche deserticola in treatment of sepsis-induced intestinal injury
10.3969/j.issn.1008-9691.2025.04.020
- VernacularTitle:肉苁蓉在脓毒症肠道损伤治疗中的潜在应用价值
- Author:
Tao MA
1
;
Libo ZHOU
;
Zhihua LI
;
Yi WANG
;
Xiaoming GAO
;
Xiangyou YU
Author Information
1. 新疆医科大学第一附属医院重症医学中心,新疆维吾尔自治区 乌鲁木齐 830054
- Publication Type:Journal Article
- Keywords:
Cistanche deserticola;
Intestinal inflammation;
Sepsis;
Intestinal motility;
Intestinal flora
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2025;32(4):493-498
- CountryChina
- Language:Chinese
-
Abstract:
In the earliest existing pharmacological monograph in China,Shennong Bencao Jing,there is a record of a parasitic plant known as"desert ginseng"——Cistanche deserticola.It exerts beneficial effects on the function of the heart,kidney,spleen,and lung.As research into its pharmacological properties has progressed,the active components of Cistanche deserticola also have shown promise for treating intestinal disorders.Due to the complex pathological mechanisms of sepsis,which often accompany multiple organ dysfunction,aligns closely with the multi-target pharmacological characteristics of Cistanche deserticola's.Furthermore,because Cistanche deserticola is both edible and medicinal,and exhibits a wide therapeutic window,it has a natural advantage in the clinical transformation and application after drug development.Currently,to expand its medicinal range,a review of the main active components of Cistanche deserticola and their related pharmacological effects is conducted,and combined with the specific characteristics of intestinal injury in sepsis,the potential value of Cistanche deserticola in intestinal barrier protection,microbial coordination,and intestinal motility regulation is further elaborated,providing new ideas and a theoretical basis for the application of Cistanche deserticola in sepsis-induced intestinal injury.
