Clinical effects of Supplemented Buyang Huanwu Decoction on postoperative patients with lumbar vertebral fracture complicated with spinal cord injury due to Qi Deficiency and Blood Stasis Pattern
10.3969/j.issn.1001-1528.2025.11.014
- VernacularTitle:加味补阳还五汤对气虚血瘀证腰椎骨折合并脊髓损伤术后患者的临床疗效
- Author:
Jia-man YANG
1
;
Tong LIU
;
De-hui FAN
;
Mei-yi SU
;
Ying LIN
;
Man-guang LIANG
;
Zhi-wen OU
;
Shun-cong ZHANG
Author Information
1. 广州中医药大学第一附属医院,广东 广州 510405;广州中医药大学博士后科研流动站,广东 广州 511400
- Publication Type:Journal Article
- Keywords:
Buyang Huanwu Decoction;
conventional treatment;
lumbar vertebral fracture;
spinal cord injury;
Qi Deficiency and Blood Stasis;
neurological functions
- From:
Chinese Traditional Patent Medicine
2025;47(11):3630-3634
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Supplemented Buyang Huanwu Decoction on postoperative patients with lumbar vertebral fracture complicated with spinal cord injury due to Qi Deficiency and Blood Stasis Pattern.METHODS One hundred and twenty patients were randomly assigned into control group(60 cases)for 6-week intervention of conventional treatment,and observation group(60 cases)for 6-week intervention of both Supplemented Buyang Huanwu Decoction and conventional treatment.The changes in clinical effects,TCM syndrome scores,spinal cord conduction signals(SEP amplitude,MEP amplitude),serum neurotrophic factors(NGF,IGF-1,BDNF),coagulation and inflammatory indices(PT,APTT,TNF-α,IL-1 β)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,TNF-α,IL-1β(P＜0.05),increased spinal cord conduction signals,coagulation and inflammatory indices(P＜0.05),and shortened PT,APTT(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with lumbar vertebral fracture complicated with spinal cord injury due to Qi Deficiency and Blood Stasis Pattern,Supplemented Buyang Huanwu Decoction can safely and effectively promote neurological function recovery.
