Research status and prospects of B cells in tumor microenvironment
10.3969/j.issn.1000-484X.2025.04.035
- VernacularTitle:肿瘤微环境B细胞的研究现状与展望
- Author:
Hongyu LU
1
;
Shenghua ZHANG
1
;
Jing HUANG
1
Author Information
1. 北京大学医学部基础医学院免疫学系,北京 100191
- Publication Type:Journal Article
- Keywords:
Tumor microenvironment;
B cell;
Immunoglobulin
- From:
Chinese Journal of Immunology
2025;41(4):985-989
- CountryChina
- Language:Chinese
-
Abstract:
Adaptive immune cells play an important role in tumor immunity.The function of T cells in tumor microenviron-ment has been studied in detail,but B cells needs to be further explored.Due to the different characteristics of producing antibodies,secreting cytokines,and presenting antigens,tumor-infiltrating B cells are divided into two phenotypes:promoting and inhibiting tu-mor proliferation.This study reviews the specific functions of B cells in the tumor microenvironment in order to explore the mechanisms of B cells involved in tumor immunity,which may provide a basis for the precision treatment targeting B cells in tumor.
