Chemical constituents from the leaves of Drynaria fortunei and their antioxidant activity
10.3969/j.issn.1001-1528.2025.08.016
- VernacularTitle:槲蕨叶化学成分及其抗氧化活性研究
- Author:
Xin CHEN
1
;
Jia-cheng WANG
;
Yan-yan LIU
;
Yong-wen ZHANG
;
Ze-jing MU
;
Hai-yan ZHANG
;
Yu PENG
;
Tong-lin WAN
;
Yong-hong LIANG
Author Information
1. 江西中医药大学现代中药制剂教育部重点实验室,江西南昌 330004
- Publication Type:Journal Article
- Keywords:
Drynaria fortunei(Kunze)J.Sm.;
leaf;
chemical constituents;
isolation and identification;
antioxidant activity
- From:
Chinese Traditional Patent Medicine
2025;47(8):2587-2592
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from the leaves of Drynaria fortunei(Kunze)J.Sm.and their antioxidant activity.METHODS ODS-AG-HG,Sephadex LH-20 and semi-preparative HPLC were used for separation and purification,then the structures of obtained compounds were identified by physicochemical properties and spectral data.The antioxidant activity was determined by DPPH mothod.RESULTS Fifteen compounds were isolated and identified as kaempferol-3-O-neohesperidoside(1),dihydrodehydrodiconiferyl alcohol(2),kaempferol-3,7-di-O-α-L-rahmnoside(3),astragalin(4),loliolid(5),trichothecene analogue(6),2,2-[bis-4-(2,3-dihydroxypropoxy)phenyl]propane(7),maculatin(8),trichothecin(9),4-[(Z)-but-2-enoyloxy]-8-chloro-12-hydroxy-7,13-epoxytrichothec-9-ene(10),8-deoxy-trichotecin(11),β-sitosterol(12),daucosterol(13),afzelin(14),samwinol(15).The IC50 values of the leaf and rhizome extracts against DPPH free radicals were(0.072±0.005),(0.287±0.012)mg/mL,respectively.CONCLUSION Compounds 1,2,5-11,15 are isolated from this plant for the first time.The leaves of D.fortunei exhibit strong antioxidant activity.
