Research Progress on Roles and Mechanisms of Short-chain Fatty Acids in Intestinal Motility
10.3969/j.issn.1008-7125.2024.09.008
- VernacularTitle:短链脂肪酸对肠道动力的作用及其机制的研究进展
- Author:
Qi CHEN
1
;
Ya JIANG
1
;
Liuqin JIANG
1
Author Information
1. 南京医科大学第一附属医院消化内科(210029)
- Publication Type:Journal Article
- Keywords:
Short-Chain Fatty Acids;
Gastrointestinal Motility;
Intestinal Microbiota
- From:
Chinese Journal of Gastroenterology
2024;29(9):559-563
- CountryChina
- Language:Chinese
-
Abstract:
Short-chain fatty acids(SCFAs)are metabolites of intestinal microbiota produced from dietary fiber fermentation.They regulate the intestinal motility through multiple mechanisms including modulation of intestinal hormones,enteric nervous system,smooth muscle cells and interstitial cells of Cajal(ICC).Alterations in SCFAs content have been observed in patients with intestinal motivity disorders.Therapeutic interventions such as SCFAs supplementation,high-fiber diets,probiotics/prebiotics,and fecal bacteria transplantation(FMT)have demonstrated efficacy in improving clinical symptoms.This article reviewed research progress on the roles and mechanisms of SCFAs in intestinal motility.
