Risk factor analysis of hypertrophic cardiomyopathy with atrial fibrillation based on cardiac magnetic resonance
10.12007/j.issn.0258-4646.2025.01.008
- VernacularTitle:心脏磁共振评价肥厚型心肌病并发心房颤动的危险因素
- Author:
Jiangyu TIAN
1
;
Lingjuan GUO
;
Dandan YANG
;
Jin GAO
;
Zhengkai ZHAO
;
Yong LIANG
Author Information
1. 成都市第三人民医院放射科,成都 610000
- Publication Type:Journal Article
- Keywords:
hypertrophic cardiomyopathy;
atrial fibrillation;
cardiac magnetic resonance;
late gadolinium enhancement;
native T1 mapping
- From:
Journal of China Medical University
2025;54(1):44-50
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the independent risk factors for hypertrophic cardiomyopathy(HCM)with atrial fibrillation(AF)based on cardiac magnetic resonance(CMR)using logistic regression analysis.Methods We reviewed 80 patients diagnosed with HCM at our hospital between January 2022 and December 2023.Statistical differences in the CMR and clinical parameters between patients with HCM with and without AF were compared.The cut-off value of HCM with AF was obtained by receiver operator characteristic curve,and binary logistic regression analysis was performed on statistically significant variables to identify independent risk factors for HCM in patients with AF.Results Univariate analysis showed that there were significant differences in the type of left ventricular late gadolinium enhancement(LGE),native T1 mapping value of the left ventricular myocardium without LGE,left atrial anteroposterior diameter,number of left ventricular LGE myocardial segments,and LGE in the basal anterior interventricular septum,mid anterior interventricular septum,and mid inferior interventricular septum were between HCM with and without AF(P＜0.05).Multivariate analysis revealed that there were significant differences in left ventricular subendocardial LGE(P=0.048,OR=5.3,95％CI:0.642-43.311),native T1 mapping value of left ventricular myocardium without LGE≥1 247 ms(P=0.03,OR=5.7,95％CI:0.734-27.41),and left atrium anteroposterior diameter 50 mm(P=0.013,OR=6.9,95％CI:1.489-31.538)between HCM with and without AF.Conclusion Left ventricular subendocardial LGE,native T1 mapping value≥1 247 ms,and left atrium anteroposterior diameter≥50 mm are independent risk factors for HCM with AF.
